The genus Calopyxis Tul. (Combretaceae) from Madagascar was included in Combretum Loefl. as sect. Calopyxis (Tul.) Jongkind in 1995. However, several species names published in Calopyxis and used in the Flore de Madagascar et des Comores are still awaiting for a combination or a synonym link in Combretum. Three names published in Calopyxis are transferred here to Combretum resulting in two new combinations and a replacement name, i.e., C. humbertianum (H. Perrier) Jongkind & Callm., C. malifolium (Bak.) Jongkind & Callm., and C. calopyxis Jongkind & Callm. Calopyxis brevistyla H. Perrier is placed into synonymy of Combretum sphaeroides (Tul.) Jongkind. Lectotypes are also designated here for Calopyxis brevistyla H. Perrier, C. malifolia Baker, C. sphaeroides Tul., and C. velutina Tul. Finally, a new species of Combretum is described from southwestern Madagascar: C. sakoense Jongkind & Callm.