As a continuation of previous studies on the subspontaneous flora of Meise Botanic Garden (MBG), this paper presents several new records of vascular plants that escaped from the garden. A total of 21 taxa not previously recorded are presented, seven of which have not been recorded before in the wild in Belgium. The naturalization status of these taxa varies from ephemeral to naturalized and potentially invasive. For each taxon, we provide information on its native distribution, invasiveness, occurrence within MBG collections and as escapes from the collections, its status in Belgium and beyond, and references to herbarium collections preserved at the Meise Botanic Garden (BR). Where relevant, additional information on related species is also given. A number of taxa are illustrated with photographs.