Laetisaria macrospora is a new species of lichenicolous Corticiaceae forming light pink to coral coloured basidiomata on Physcia adscendens and P. stellaris. The basidiomata are usually located on the lower surface of the host thallus and produce basidia with four sterigmata and relatively large basidiospores, 23-34 x 11-18 mu m. Phylogenetic analyses using nuITS sequences fully support the placement of the new species in Laetisaria, a genus that is recovered as monophyletic. Laetisaria macrospora was discovered in the Massif Central (France) in lichen communities growing on branches of Juniperus and Genista at the summit of the Puy de Manson.